Normalization and Rarefaction in Gene Discovery
A way to save time, money and frustration in searches for specific genes have been found by researchers at Purdue University, It can shed light on the biological processes associated with all forms of life. The work finished by Andrew DeWoody, a professor of genetics, and postdoctoral associate Matthew C. Hale, they have provided evidence that a step called normalization is no longer necessary with recent advances in DNA sequencing technology. Instead, they used a theoretical approach called rarefaction for gene discovery, a process developed for ecological surveys to determine the abundance of a species in an ecosystem. The results were published in the journal BMC Genomics. 阅读全文 »
