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Web2.0 Release

Hello! I am Liuyw, Welcome! Here will release sharing Web 2.0 platform.

Human telomeres function as a protective structure capping both ends of the chromosome. They are composed of long, repetitive sequences of TTAGGG, associated with a variety of telomere-binding proteins. Telomeres protect the chromosomes from end-to-end fusion, recombination, and degradation, all events that can lead to cell death. At cell replication, telomeres cannot be completely replicated. They are gradually shortened, and when the telomeres reach a critical threshold, cell replication is arrested in what is called “replicative senescence.” Thus, telomeres act as an intrinsic “counting” mechanism of the cell’s aging process. Telomerase is an enzymatic ribonucleoprotein complex that acts as a reverse transcriptase in the elongation of telomeres. Telomerase activity is almost absent in somatic cells, but it is detected in embryonic stem cells and in the vast majority of tumor cells. Tumor cells, in fact, may contain short and stable telomeres that confer immortality to the cancer cells, which are thus able to replicate indefinitely. The deregulation of telomeres thus plays an important role in the relationship between premature aging syndrome and cancer. This review describes the recent advances in the molecular characterization of telomeres, the regulation of telomerase activity in cancer pathogenesis, and the potential of targeting telomerase for cancer therapy.

The value of Franchise

Posted on October 21, 2009

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The greatest contribution of Warren E. Buffett for investment theory’s lies in its awareness of the franchise value. He excavated the value of franchise, then all of those has greatly expanded the connotation of value investing.

Despite the high success rate of franchising, but it is not suitable for everyone. Now let me talk about investors how to select franchise business.

Today, it’s full of opportunities and risks in markets, franchise are the same. If you master the relevant knowledge, you will get the real market opportunity. But if you ignore those knowledge, you will be suffered. Assessment of franchise Boston, MA, on the one hand, the general business knowledge remains important, on the other hand, investors need to understand the difference between the franchise.

Google removed pagerank

Posted on October 18, 2009

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According to insiders disclose, Google Labs released version of webmaster tools, while quietly removed the reptile part of the statistics of the PageRank. However, until now Google has not released official statement.

Google has another investment. Today, Adimab, Inc., announced the closing of a Series D financing led by Google Ventures with participation by previous investors Polaris Ventures, SV Life Sciences, OrbiMed Advisors and Borealis Ventures. Bill Maris of Google Ventures will join Adimab’s Board of Directors. The total amount of the financing was not disclosed.